
Enneking Staging System
Benign Lesions
- Latent lesion
- (HOOG) Hemangioma, Osteoid Osteoma, Osteochondroma, Granuloma Eosinophilic
- Observation
- Mx: intralesional excision +/- adjuvants (liquid nitrogen, phenol, PMMA)
- Active lesion
- (HOOOGA) Osteoid osteoma, osteochrondroma, hemangioma, eosinophilic granuloma, ABC
- Mx: en bloc resection vs intralesional excision +/- adjuvants (liquid nitrogen, phenol, PMMA)
- Aggressive lesion
- GCT, osteoblastoma
- Mc: wide excision (cuff of normal tissue)
Malignant Lesions
- Low grade
- High grade
- Metastatic
- Intracompartmental
- Extracompartmental
DDx Categories
Age, Location, Size
Age
Young 10-30
Middle 30-50
Older 50+
Location
Bone (Vertebrae)
- Anterior (more malignant)
- Myeloma
- Ewings
- Osteosarcoma
- Posterior (more benign)
- OOGA
Non-Bone (Spinal Cord)
- Intradural Extramedullary
- Schwannoma
- Meningioma
- Intradural Intramedullary
- Ependymoma
- Astrocytoma
- Usually benign
- Intramedullary mets -> <3mo life expectancy
- Extradural
- Metastasis
- Extramedullary
- Drop mets via CSF
- Intramedullary
- Extramedullary
- Lymphoma
- T2 hyperintense with marked homogenous contrast
- Treatment: methotrexate
- Metastasis
Scenarios and Responses
- No current Ca Hx (includes people with no current Ca but +ve remote Ca Hx), Painful spine lesion in <40 – refer to ortho onc; likely biopsy
- No current Ca Hx (includes people with no current Ca but +ve remote Ca Hx), Painful spine lesion in >40 – do mets staging workup because probably mets, but need to confirm
- Current Ca Hx no fracture, Mirel Score <9 staging workup, bisphosphonates or denosumab to reduce risk of fracture
- Current Ca with Impending Fracture – curretage with cement, fix hip to femur, post op rads
- Path Fracture – Staging workup – core needle
Mirel Score – fix if >9
- Location
- Upper
- Lower
- Pertroch
- Pain
- Non
- Moderate
- Functional
- Lesion
- Blastic
- Mixed
- Lytic
- Size
- 1/3
- 2/3
- 3/3